Category ALDX

Aldeyra Therapeutics Inc

Aldeyra ( $ALDX ) : 3 attempts were not enough

I deliberately waited at least one full day before writing this piece. Not to stall, but to look at the March 17, 2026 Complete Response Letter with a colder head, outside the immediate chaos of the tape. What follows is not a quick reaction article. It is a long-form reconstruction of how Aldeyra reached a third rejection in dry eye disease, why that matters far beyond one bad headline, where management deserves a tougher standard, and whether any credible path still exists for reproxalap in DED.

Aldeyra Therapeutics ( $ALDX ): past, present and future around reproxalap and the March 2026 FDA decision

A long-form bilingual deep dive built around the full regulatory arc of Aldeyra, from the first dry-eye filing to the 2025 collapse and the current March 2026 binary setup. The focus here is not only on what happened, but on why the market still cares, what could realistically change if reproxalap is approved, what the damage would look like if it is rejected again, and how retail traders are framing the setup in the final stretch before the decision.

Aldeyra Therapeutics (ALDX) PDUFA March 2026

Aldeyra Therapeutics (NASDAQ: ALDX) is a clinical-stage biotechnology company developing modulators of reactive aldehyde species (RASP) for immune-mediated and metabolic diseases. The key late-stage asset is reproxalap, an ophthalmic RASP modulator for dry eye disease (DED) and allergic conjunctiviti

ALDX Aldeyra Therapeutics Inc Update dec 16

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On December 16, 2025, the FDA formally extended the PDUFA target action date for reproxalap in dry eye disease from December 16, 2025 to March 16, 2026, after Aldeyra submitted the Clinical Study Report (CSR) for its dry-eye field trial to the NDA at the FDA’s request.

ALDX Aldeyra Therapeutics  Update dec 12

Aldeyra Therapeutics is a clinical-stage biotech focused on inflammation, oxidative stress and ocular / metabolic diseases via its RASP platform. The lead asset, Reproxalap, is currently under FDA review for dry eye disease with a target action date of December 16, 2025 — a highly binary event coming after previous Complete Response Letters (CRLs) in 2023 and 2025.